Restylane® Refyne is designed with XpresHAn Technology™ to help soften laugh lines (nasolabial folds and marionette lines). This can help you restore a more natural look to your face while maintaining your facial expressions.1-4 So, you always look like you. Talk to your specialist and see for yourself why it’s worth it.
As skin loses elasticity with age, the lines that run from the sides of your nose toward the corners of your mouth (nasolabial folds) and the lines that run from the corner of your mouth toward the chin (marionette lines) appear more noticeable. Restylane Refyne is a specifically formulated hyaluronic acid dermal filler made with XpresHAn TechnologyTM† that helps correct these lines for a more natural look to your face.3,4 The unique cross-linking of the gel in Restylane Refyne is also designed to help support your natural expression—for real-life results that help maintain natural movement when you're smiling, frowning and even puckering up.1,2
† XpresHAn Technology™ is known as Optimal Balance Technology outside the US. Restylane Refyne is known as Emervel® Classic and Restylane Defyne is known as Emervel® Deep outside the US.
In a clinical study, subjects were evaluated based on perception of the naturalness of facial expressions in motion after 1 month of Restylane Refyne and Restylane Defyne optimal treatment.1-3
were satisfied with their treatment results1*
would do the treatment again1*
would recommend the products to a friend1*
Restylane Defyne and Restylane Refyne are the only fillers on the market that have been shown in a clinical study to help maintain movement and expressions.1
*This was a multicenter, noncomparative trial of subjects aged 35-65 years (N=63). Subjects were evaluated based on the perception of the naturalness of facial expressions in motion after 1 month of Restylane Refyne and Restylane Defyne optimal treatment. Pooled results for both Restylane Refyne and Restylane Defyne subjects.1
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The Restylane family of products includes Restylane®, Restylane-L®, Restylane® Lyft with Lidocaine, Restylane® Silk, Restylane® Refyne, and Restylane® Defyne. Restylane® and Restylane-L® are for mid-to-deep injection into the facial tissue for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds. Restylane® and Restylane-L® are also indicated for injection into the lips in patients over the age of 21.