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See where Restylane® products can help reduce your facial wrinkles.
Actual patient. Individual results may vary.
Introducing Restylane® Refyne & Restylane® Defyne, two hyaluronic acid gel fillers for laugh lines (nasolabial folds & marionette lines) made with XpresHAn Technology™ that maintains natural expression in motion. So your smiles, laughs, frowns and kisses looks natural and supported.1-4
What is Restylane? Natural-looking results1

With over 30 million treatments worldwide and counting,5 the Restylane line of hyaluronic acid fillers provides natural-looking results by smoothing away facial wrinkles and folds (Restylane,8 Restylane Lyft,9 Restylane Refyne,2 Restylane Defyne3), providing subtle lip enhancement (Restylane,8 Restylane Silk10) and smoothing the lines around the mouth (Restylane Silk10), and adding lift and volume to the cheeks (Restylane Lyft9).

Look Your Naturally Expressive Best

Introducing Restylane Refyne and Restylane Defyne

Made with XpresHAn Technology, Restylane Refyne and Restylane Defyne help offer just the right amount of lift to laugh lines (nasolabial folds and marionette lines)—all while preserving your ability to show your range of natural facial expressions.1-4

Actual patient. Individual results may vary.
Restylane® Refyne and Restylane® Defyne Are Worth Every Expression
Skin Science How Restylane works

The Restylane line of products is formulated to act like your body's own naturally occurring hyaluronic acid, restoring volume to your skin.2,3,5

NASHA© Technology

Restylane Silk, Restylane and Restylane Lyft use our innovative NASHA technology. This gives each product a unique particle size for tailored treatment.11

Designed to act like natural hyaluronic acid, Restylane® can treat moderate to severe facial wrinkles and folds. Finer particles
for fine wrinkles and
detailed shaping
Restylane® (hyaluronic acid) and NASHA® technology can help reduce moderate to severe facial wrinkles. Medium-sized particles
for moderate to severe
wrinkles and folds
Restylane®’s NASHA® technology and hyaluronic acid treat moderate to severe facial wrinkles and folds. Larger particles for
severe wrinkles and
greater volume

XpresHAn TechnologyTM

Restylane Refyne and Restylane Defyne are flexible hyaluronic acid gels designed to give you the flexibility to show your natural range of facial expression.1-3,7

Learn more about more Galderma® aesthetic treatments for frown lines between the eyebrows and collagen stimulation.

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Actual patients. Individual results may vary.

The Restylane family of products includes Restylane®, Restylane-L®, Restylane® Lyft with Lidocaine, Restylane® Silk, Restylane® Refyne, and Restylane® Defyne. Restylane® and Restylane-L® are for mid-to-deep injection into the facial tissue for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds. Restylane® and Restylane-L® are also indicated for injection into the lips in patients over the age of 21.