Defyne your look
from every angle

Crafted with XpresHAn Technology™, Restylane® Defyne helps smooth out deep laugh lines (nasolabial folds and marionette lines) as well as enhance chin projection. Using innovative cross-linking technology, Restylane Defyne is a hyaluronic acid dermal filler that is able to help restore a more youthful, natural-looking appearance, while helping you maintain your natural expressions and movement.1-4

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Actual patient. Individual results may vary.

before + after

These images are unretouched photographs of actual patients who have used Restylane Defyne to achieve natural-looking results.

Before + After Chin Results

Restylane Defyne showed clinically proven safety and lasting results for chin enhancement for up to 1 year after the last injection.5

Before + After Nasolabial Folds and Marionette Lines

Restylane Defyne is clinically proven to smooth moderate lines and provide the right amount of support and flexibility through a range of facial expressions.1,4

What is

Restylane Defyne?

As we age, our skin loses elasticity. This causes the lines that run along the side of the face and mouth (nasolabial folds and marionette lines) to become more pronounced as well as the chin to recede so far back toward the neck that it creates an imbalance of facial features (chin retrusion).6,7 Restylane Defyne is crafted with XpresHAn Technology™ to correct these deepened lines and wrinkles and improve chin projection by correcting mild-to-moderate chin retrusion. The unique cross-linking of the gel in Restylane Defyne is also designed to help support your facial expressions—for natural-looking results that help maintain your natural movement.3,4

Make every expression worth it with Restylane® Defyne8
Actual patient. Individual results may vary.
Actual patient. Individual results may vary.
What is

chin retrusion?

When the chin recedes so far back toward the neck that it creates an imbalance of facial features. This is known as “weak chin,” which is only noticeable from the side.6,7

No chin retrusion
No retrusion
Mild chin retrusion
Mild retrusion
Moderate chin retrusion
Moderate retrusion
Substantial chin retrusion
Substantial retrusion

Restylane® Defyne is indicated for augmentation of the chin region to improve the chin profile in patients with mild to moderate chin retrusion over the age of 21.

Chin retrusion pen test

Do I have chin retrusion?

Try this:

Take a pen and hold it going from your nose to lower lip to chin. The ideal chin should only be a few millimeters behind that line—any farther back and you may have chin retrusion.


for the lower face

Natural-looking treatments with minimal to no downtime and long-lasting results*

What are nasolabial folds?
Restylane Defyne for nasolabial folds
What are marionette lines?
Restylane Defyne for marionette lines
What is chin retrusion?
Restylane Defyne for chin augmentation and correction of mild-to-moderate chin retrusion
Restylane Defyne Indication areas
Restylane Defyne for nasolabial folds
Restylane Defyne for chin augmentation and correction of mild-to-moderate chin retrusion
Restylane Defyne for marionette lines

*Up to 1 year.

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Real Results

In clinical studies, subjects' satisfaction was evaluated following treatment results.


of patients were satisfied with how their
DEFYNE-ed chin looked proportional to
the rest of their face5†


were satisfied with the
treatment of their nasolabial
folds and marionette lines1‡

Restylane products with XpresHAn Technology™ (Restylane Defyne, Restylane Refyne, and Restylane Kysse) are the only fillers that have been shown in a clinical study to help maintain movement and expressions.4

  • FACE-Q rating of "very satisfied" or "somewhat satisfied" with questions.5
  • This was a multicenter, noncomparative trial of subjects aged 35-65 years (N=63). Subjects were evaluated based on the perception of the naturalness of facial expressions in motion after 1 month of Restylane Defyne and Restylane® Refyne optimal treatment. Pooled results for both Restylane Refyne and Restylane Defyne subjects.1
Find a


ReDefyning your lower face starts with finding a quality specialist to do it. Fill out the simple form below to find an injector in your area.

Before Restylane® Defyne (hyaluronic acid) Restylane® Defyne (hyaluronic acid) results Before Restylane® Defyne (hyaluronic acid) After Restylane® Defyne (hyaluronic acid) After Restylane® Defyne (hyaluronic acid)

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Offer terms and conditions apply. Please contact this practice for complete details.

The Restylane family of products are indicated for patients over the age of 21, and includes Restylane, Restylane-L®, Restylane® Lyft with Lidocaine, Restylane® Silk, Restylane® Kysse, Restylane® Refyne, Restylane® Defyne, and Restylane® Contour.

Restylane® and Restylane-L® are for mid-to-deep injection into the facial tissue for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds. Restylane® and Restylane-L® are also indicated for injection into the lips.

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