Crafted with XpresHAn Technology™, Restylane® Defyne helps smooth out deep laugh lines (nasolabial folds and marionette lines). Using innovative cross-linking technology, Restylane Defyne is a hyaluronic acid dermal filler that is able to help restore a more youthful, natural-looking appearance, while helping you maintain your natural expressions.1-3
As we age, our skin loses elasticity and the lines that run from the sides of the nose toward the corners of the mouth (nasolabial folds) and the lines that run from the corner of your mouth toward the chin (marionette lines) become more pronounced. Restylane Defyne is crafted with XpresHAn TechnologyTM† to correct these deepened lines.3 The unique cross-linking of the gel in Restylane Defyne is also designed to help support your facial expressions—for natural-looking results that help maintain your natural movement.1
†XpresHAn Technology™ is known as Optimal Balance Technology outside the US. Restylane Refyne is known as Emervel® Classic and Restylane Defyne is known as Emervel® Deep outside the US.
In a clinical study, subjects were evaluated based on perception of the naturalness of facial expressions in motion after 1 month of Restylane Defyne and Restylane Refyne optimal treatment.1*
were satisfied with their treatment results1*
would do the treatment again1*
would recommend the products to a friend1*
Restylane Defyne and Restylane Refyne are the only fillers on the market that have been shown in a clinical study to help maintain movement and expressions.1
*This was a multicenter, noncomparative trial of subjects aged 35-65 years (N=63). Subjects were evaluated based on the perception of the naturalness of facial expressions in motion after 1 month of Restylane Defyne and Restylane Refyne optimal treatment. Pooled results for both Restylane Refyne and Restylane Defyne subjects.1
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The Restylane family of products includes Restylane®, Restylane-L®, Restylane® Lyft with Lidocaine, Restylane® Silk, Restylane® Refyne, and Restylane® Defyne. Restylane® and Restylane-L® are for mid-to-deep injection into the facial tissue for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds. Restylane® and Restylane-L® are also indicated for injection into the lips in patients over the age of 21.