New Product

Defyne your expression.

Invest in yourself with real-life results that help maintain natural movement to help keep you looking like you1,2

Crafted with XpresHAn Technology, NEW Restylane® Defyne helps smooth out deep laugh lines (nasolabial folds and marionette lines). Using innovative cross-linking technology, Restylane Defyne is a hyaluronic acid dermal filler that is able to help restore a more youthful, natural-looking appearance, while helping you maintain your natural expressions.1,2

Actual patient. Individual results may vary.

Natural-Looking

before + after

These images are unretouched photographs of actual patients who have used Restylane Defyne to achieve natural-looking results.

What is Restylane Defyne?

As we age, our skin loses elasticity and the lines that run from the sides of the nose toward the corners of the mouth (nasolabial folds) and the lines that run from the corner of your mouth toward the chin (marionette lines) become more pronounced. Restylane Defyne is crafted with XpresHAn Technology to correct these deepened lines.3 The unique cross-linking of the gel in Restylane Defyne is also designed to help support your facial expressions—for natural-looking results that help maintain your natural movement.1,2

XpresHAn Technology is known as Optimal Balance Technology outside the US. Restylane Refyne is known as Emervel® Classic and Restylane Defyne is known as Emervel® Deep outside the US.

See

Real Results

In a clinical study, subjects were evaluated based on perception of the naturalness of facial expressions in motion after 1 month of Restylane Defyne and Restylane Refyne optimal treatment.1*

97% 61/63 treated
subjects

were satisfied with their treatment results*

97% 61/63 treated
subjects

would do the treatment again*

95% 60/63 treated
subjects

would recommend the products to a friend*


Restylane Defyne and Restylane Refyne are the only fillers on the market that have been shown in clinical trials to help maintain natural movement and expressions.1,2,4

  • *This was a multi center, noncooperative trial of subjects aged 35-65 years (N=63). Subjects were evaluated based on the perception of the naturalness of facial expressions in motion after 1 month of Restylane Defyne and Restylane Refyne optimal treatment.1

Find a

Specialist

Rewards & Savings

Join ASPIRE Galderma Rewards and treat yourself to an exclusive experience that will help you look your best every day.

  • Multiple ways to earn points
  • Rewards include Galderma® treatments and offers from retail favorites Sephora® and Nordstrom®

It’s easy to join and easy to enjoy — sign up today, and you’ll receive a $20 treatment certificate.

$20   Treatment
Certificate
Join Now
Actual patients. Individual results may vary.
Before Restylane® Defyne (hyaluronic acid) Restylane® Defyne (hyaluronic acid) results Before Restylane® Defyne (hyaluronic acid) After Restylane® Defyne (hyaluronic acid)

The Restylane family of products includes Restylane®, Restylane-L®, Restylane® Lyft with Lidocaine, Restylane® Silk, Restylane® Refyne, and Restylane® Defyne. Restylane® and Restylane-L® are for mid-to-deep injection into the facial tissue for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds. Restylane® and Restylane-L® are also indicated for injection into the lips in patients over the age of 21.