The Restylane Family of products includes Restylane, Restylane-L, Perlane, and Perlane-L. These products can be used individually to add volume and fullness to the skin to correct moderate to severe facial wrinkles and folds, such as the lines from your nose to the corners of your mouth (nasolabial folds). Ask your healthcare professional which is right for you.

Important Safety Considerations for the Restylane Family of products
Products in the Restylane Family should not be used by people with previous bad allergies, particularly to certain microorganisms known as gram-positive bacteria, or by people with previous bad allergies to drugs who have required in-hospital treatment. These products should not be used by people with bleeding disorders. Injections should not be made anywhere except the skin or just under the skin. Restylane-L and Perlane-L should not be used by people with a known allergy to lidocaine.

Use of products in the Restylane Family at the site of skin sores, pimples, rashes, hives, cysts, or infection should be postponed until healing is complete. Use of the products in these instances could delay healing or make your skin problems worse. After your treatment, you might have some swelling, redness, pain, bruising, and tenderness. This will normally last less than seven days. In rare circumstances, the doctor may inject into a blood vessel, which can damage the skin. Although rare, red or swollen small bumps may occur. If you have had facial cold sores before, an injection can cause another outbreak. To avoid bruising and bleeding, you should not use the products if you have recently used drugs that thin your blood or prevent clotting. If you are pregnant, breastfeeding, or under 18 years of age, you should not use products in the Restylane Family.

Patients should be limited to 6.0 mL per treatment. The safety or effectiveness of products in the Restylane Family for the treatment of anatomic regions other than nasolabial folds has not been established in controlled clinical studies.

The Restylane Family of products is available only through a licensed practitioner.

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